Feeling contact from Oleksandr Zinchenko, who was also to blame for Pierre-Emil Hojbjerg's equaliser at 1-1, Ward-Prowse went down asking the referee for a spot-kick - but no decision was forthcoming.
They lead Pep Guardiola's men by seven points ahead of their trip to Manchester but Klopp is unconcerned by the prospect of further increasing their advantage.
"So we look at ourselves, and tomorrow against Southampton, we have to do what we do, and try to win, and when that happens, everything comes back to a normal position". But Xherdan Shaqiri said that winning was the sole motivation.
Even though they were deprived of the services of the 27-year-old, City still managed to prevail past Southampton as they bounced back having lost their previous two league matches.
Benjamin Mendy's knee injury and Fabian Delph's red card at Leicester necessitated Zinchenko's latest free-form interpretation of the left-back role, but right-back has also been a problem for City of late, with Kyle Walker turning in a succession of exhausted performances. Oleksander Zinchenko's error could have proved costly against Southampton and facing Mohammed Salah will be a much bigger step-up in quality for the Ukrainian. I'm sure when we keep going like this we are going to be very successful. He was given a couple of problem moments from Austin.
After surviving a Southampton penalty appeal, the visitors regained control just before the break. Fernandinho is back in midfield, while Bernardo Silva and David Silva play.
Regardless of the result, however, Guardiola's side still weren't at their best: suspect at the back and, at times, too confident in possession, suggesting they could be victims of high-pressing triggers. We missed a lot of chances. Sergio Aguero is up front. His first Premier League goal in six weeks.
Sean Dyche dropped former England number one goalkeeper Joe Hart to the bench for the first time in the league this season and was rewarded with a rare clean sheet as first half goals from Chris Wood and Dwight McNeil secured a vital three points.