He's already seen his insurance premiums sky-rocket and says he doesn't "want to be in a high-risk pool". "That race was swung by Donald Trump to DeSantis, who's now behind".
DeSantis used Trump's backing to make the case that if he is elected, the state will be in a better position to receive support from Washington, D.C., in contrast to Gillum who has called for the impeachment of the president.
Gillum voted early after attending a "Bring It Home Midnight Rally" at the campus of Florida A&M University with Sean "Diddy" Combs.
He also thanked Trump for standing by him "when it wasn't necessarily the smart thing".
Gillum had pulled off an upset in the Democratic primary, winning the nomination after consistently polling in third for most of that race, but he was unable to carry that same momentum into the general election.
"That's just who he is".
"I voted for you", she replied. "And that's unfortunate, but we gotta keep trying".
After his concession speech, supporters hugged one another.
DeSantis, meanwhile, has been warning voters about the Tallahassee mayor's association with Dream Defenders, a radical far-left group associated with Palestinian terrorism. Those issues, which were already bubbling up throughout the primary, were escalated by DeSantis when he went on Fox News a day after becoming the nominee to warn Florida voters not to "monkey this up" by electing Gillum.
Though it turns out, these events didn't hurt DeSantis enough to sway things in Gillum's favor.
In Michigan, Democrat Gretchen Whitmer turned back Republican Bill Schuette in the contest to replace Republican Governor Rick Snyder, who could not run again due to term limits. Marco Rubio made a decision to run for re-election. The 40-year-old is pro-gun, anti-immigration, anti-LGBTQ, and anti-women's rights.
Watch the clip above, via Fox News. And after a comeback win in the primary himself, DeSantis faced off against an opponent whose primary victory surprised the entire state - which meant his campaign had to build a strategy against Gillum one day at a time, observers noted. Trump joined in, tweeting similar messages.
DeSantis argued throughout the campaign that Florida's relationship with the president - whether he or she agrees with his policies or not- is important for the state.
In recent days, developers Don Peebles and Jeff Greene each gave $100,000 to Forward Florida, a political action committee supporting Gillum.
As Trump tried to help DeSantis, Former President Barack Obama and former Vice President Joe Biden held rallies to aide Gillum and Sen. Gillum even spelled out the slur during a debate.
"Now, I'm not calling Mr. DeSantis a racist". I'm simply saying the racists believe he's a racist, ' he said.
DeSantis defended Trump as the campaign closed.