However, he later left to have further tests done, a statement from Barcelona later confirming a fracture of his radius bone.
Forward of "Barcelona" Lionel Messi received a severe injury in the championship match Spain against "Seville" (4:2).
The Argentine - who had set up Philippe Coutinho's opening goal after two minutes and himself added a sublime second after 12 minutes - struggled to play on before being substituted in the 26th minute.
This is a game in which Barcelona wouldn't really miss Messi's presence, considering he would have made way for the bench warmers, anyway.
Real Madrid was four points behind Barcelona, in fifth place.
The 31-year-old could only last 26 minutes on the pitch before he was being replaced with France global Ousmane Dembele.
The hosts then went down the other end and scored a fourth, with Rakitic's super volley finding the back of the net to secure all three points.
"We have to prepare ourselves, it is clear we are going to notice the loss of Messi but we have players that can cover".
However, coach Ernesto Valverde isn't the only one with injury headaches, as counterpart Luciano Spalletti will be facing an anxious week or so after the Derby della Madonnina on Sunday night took its toll on his players. Suarez buried the penalty.
Lopetegui needs his team to rebound immediately with a winning streak, starting against Viktoria Plzen on Tuesday and at Barcelona.
Asked about his future, Lopetegui said: "It is the last thing I am thinking about".