Two to five inches of snow are possible in the Eastern Panhandle counties of Berkeley and Jefferson.
Some wet snow may also fall on the zone from Washington, D.C., to Philadelphia and perhaps as far north as New York City on Monday.
The storm will move into the Northeast overnight into Monday morning.
In Connecticut, the wet snow blanketed roads and made for a hard morning commute.
The snow should mostly end Saturday morning in northern Minnesota, about 8 a.m in the Twin Ports, and will be out of Northwestern Wisconsin before noon.
Snow poured down on the U.S. city in the early hours of this morning, with yesterday's temperatures of 60°f plummeting to nearly 30°f.
A Winter Storm Watch means heavy snow, up to 6 in.in this case in local areas, along with sleet or ice accumulations are possible. The latest storm follows a string of nor'easters that hit the East Coast in March, with heavy snows and damaging winds that knocked out power to more than 2 million customers at their peak.
The snow is expected to taper off late this morning, giving way to partly sunny skies later this afternoon. It will feel almost 40 degrees colder on Monday morning. Strong winds also continue across the region and a wind gust of up to 68 miles per hour was recorded at the Rapid City Airport in South Dakota late Friday.
The cold air on Monday makes it down into the Southern Plains and Tennessee River Valley with wind chills in the 30s.
Parts of the Midwest and interior Northeast will have the best chances for snow. Temperatures are expected to plunge well below average again beginning Thursday, with the cold pushing straight into the weekend.