Titans QB Marcus Mariota officially ruled out for Week 5

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Campbell's last score was an 81-yard run that gave the Oilers their final points in their 35-30 victory. Looking ahead, Mariota is no lock to return in time for the Titans' Week 6 contest on October 16 against the Colts, with Ian Rapoport of NFL.com having suggested that the recovery time for the hamstring injury Mariota suffered back on October 1 "estimated to be 2-4 weeks".

At 2-2 with an injured quarterback, the Titans find themselves in an unideal situation.

The Dolphins will make a delayed home debut after their season opener against Tampa Bay was postponed due to Hurricane Irma. As if that weren't enough, they had to do so after an embarrassing loss to division foe the New York Jets. Cassel will need to handle the ball more carefully. "I've played against the group of guys the last couple years". The Miami offense is just a mess and I don't see them fixing all of their issues after a game in London.

Facing off against the Texans defense was something which the Titans weren't ready.

"The way we're playing offensively, I don't think we can take anything for granted right now", Cutler says. They've been out-scored 40-7 in those games.

The start could be critical.

Murray, on the other hand, after getting half the Jacksonville game and two practices off, was back and rolling with his best effort of the season two weeks ago against the Seahawks. Reese said. "Brandon Weeden comes in here and knows what he has to do is he has to conform exactly to whatever it is they want". The Titans are a strong team. They're averaging 138.8 yards rushing, which ranks sixth. But Mariota just ran for two TDs for the first time in his career, the franchise's first quarterback with two TDs rushing since Steve McNair against New England on October 5, 2003.

Miami Pro Bowl defensive tackle Ndamukong Suh looks forward to tackling the challenge. "I kind of worry about me and kind of go from there".

"It's my job week in to week out to be prepared, be accountable, but the mental reps is one thing and also going into a game you never know when your opportunity's going to come up", Cassel said. "I enjoy it. I can't wait". Their run defense has been good, allowing just 77.7 yards per game on the ground. That's compared with last year's 4.8 average, worst in the league.

Cordrea Tankersley is on an accelerated learning curve, and he must improve dramatically week over week to continue justifying his stranglehold on the starting cornerback position on the opposite side of Xavien Howard. And that's what we're looking for from Marcus. How long are we going to be on the field?

Maxwell was listed as questionable on the Dolphins injury report.

Marcus Mariota made 15 starts for the Titans last season, completing 61.2 percent of his passes and throwing for 3,426 yards, 26 touchdowns and nine interceptions. In fact, the quarterback may not even miss a game. Jay Cutler threw for 164 yards and a touchdown on 20 of 28 passing, while Jay Ajayi led the team with 12 carries for 46 yards.

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