The unified IBF and WBA challenge will take place at the Principality Stadium in Cardiff.
"I can see Joshua wanting to get some rounds in but you just don't know, it could be over when he wants it to be over".
In round ten, Joshua landed a good combination, and referee Phil Edwards stopped the bout at 1:34.
Takam, who has lost three times, is a late substitute for the Bulgarian Kubrat Pulev, who pulled out of the fight earlier this month with a shoulder injury.
"I'm not in a rush to go anywhere". He recognises that the victory over Klitschko and his status since then has led to an even wider following, dominated by a more casual fan.
Joshua worsened the gaping wound with more thudding punches in the fifth, while a jolting uppercut had Takam on unsteady legs in the sixth, although he somehow remained on his feet and shared a defiant stare with his attacker.
Any worries fans might have had about Joshua being able to box effectively late in fights at the start of the year were answered when he nearly went the distance against Klitschko.
The rest of the card is full of solid matchups, especially if you're a fan of British boxing.
After the previous round AJ's corner has clearly told him to calm down after he stepped on the gas. I like fighting in London, in the UK.
Joshua had predicted that he'd struggle to put Takam away due to his head which was like "a block of cement" and he found out just how durable the 36-year-old's skull was through rounds five, six and seven as Takam refused to wilt despite an additional cut to his left eye.
Round 10: Legs are crossed, trying to relieve the pain of holding in this piss.
But he finished the stanza well and Takam briefly hit the canvass after being caught by a left hook.
Lai Mohammed, the minister of information and culture, is also on the federal government's entourage.
He said on Friday, the idea of unifying the title was a "great challenge".