Manager Jorge Sampaoli has shown a preference for starting both men behind a focal point centre-forward of late, though the Albiceleste have majorly struggled for goals, leading to questions surrounding whether Messi and Dybala should share the pitch together at all.
"They've lost a lot but they're a team who must be respected". Dybala sent his effort well over from just inside the area before Messi curled an effort against the post after finding space at the top of the box.
Barcelona defeated Juventus in the 2015 Champions League final. He is at an age [33-year-old] in which if he plays many games in a row, we have to keep that in account, but not only with him, also Busquets, Rakitic.
The most expensive player in the world Neymar and his Paris Saint-Germain travel to Scotland to meet the Scottish champions Celtic.
Things certainly worked well at the weekend.
The 30-year-old opened the scoring on the stroke of half time before creating one for Ivan Rakitic and scoring another of his own as Barca laid down an early marker in this season's competition. In last season's Champions League Dembele's assist count was five.
Now, Juventus face a an uphill test in the in-form Barcelona, and considering the hosts have won 15 and drawn one of their last 16 home games in the Champions League, THT predicts a nail-biting game which is ultimately likely to result in a 2-1 victory for the Spanish giants.
But three games into the season, Barcelona has a ideal record and Madrid has only one victory.
After losing to Juve, much was made of the fact that Messi had never scored against Gianluigi Buffon, while the Argentine also failed to hit the target over two legs as Barca were beaten 5-1 by fierce rivals Real Madrid in August. He has seven goals so far this season.
It kicks off at Camp Nou at 19.45 United Kingdom time (18.45 GMT), follow the build-up and action from this game and Roma-Atletico Madrid on the LIVEBLOG.
Valverde has already experienced the ups and downs of his new role just over a month into the season as his reign started with a 5-1 thrashing by Madrid in the Spanish Super Cup before a run of four straight victories.
"Juventus are a very strong team".