While the picture doesn't outrightly reveal anything about her role in the movie, Domino strategically placed on Deadpool could indicate that there will conflict through the movie.
"The latest updates and spoilers for "#Deadpool 2" will feature a possible appearance at #New York Comic-Con and a first look at the mutant mercenary Domino in the movie. The character will be played by Zazie Beetz (Atlanta) in the forthcoming film, which is now shooting up in Vancouver, Canada with Ryan Reynolds returning as the title character. She, through her psychic powers, can affect the probabilities of making things work in her favour and against others. The character has been directly connected to Cable in the Marvel comics, which is pretty fitting since - again - Cable is in Deadpool 2... too, played by Josh Brolin (No Country for Old Men). Basically, she's supernaturally lucky.
Leitch added: "He's such a great actor, he brings a humanity to Cable, but he also has the depth of acting chops to hang with the comedy when needed". In case you weren't sure Deadpool 2 was going to be the sequel, Domino is posed the same way as well. As a diehard Domino fan of 25 years, I can tell you that yes, yes we do need another Deadpool movie-especially since it's giving us a live-action version of one of the X-Men's toughest associates.
After Ryan Reynolds blew fans away with his performance in Deadpool, all eyes turned to the film's inevitable sequel, Deadpool 2.
It's this connection that gives us our best insight into how Deadpool and Domino will cross paths in the new film. She's also shared romantic relationships with both Cable and Wolverine. The image is a play on one Reynolds posted in 2015 to promote the first film, which itself was a parody of an image of a naked Burt Reynolds for a Cosmopolitan centerfold in 1972.
Deadpool 2 now has a 4.07 out of 5 ComicBook.com User Anticipation Rating, making it the fifth most anticipated upcoming comic book movie among ComicBook.com readers.