But if one or more of their best players go down with injuries, there isn't an equal amount of talent waiting in the wings.
One concern amongst the fan-base is the lack of arrivals this summer.
Spurs are the only team in the top flight yet to make a signing in the current transfer window and have sold England right-back Kyle Walker to Manchester City for a fee reported at 50 million pounds ($64.97 million) by local media.
What business? At the time of this writing, Spurs have brought in a total of zero additions to the squad, and their only transfers have been outgoing. Rafa mentioned earlier last week that the side that he selected to play last weekend will be near enough the side that will be selected to face Spurs which means that Gayle is likely to miss out and Mitrovic will be playing up front or Ayoze Perez. What they must do though, is add a little depth before September.
Fantastic, an oblivious spectator may assume.
He continued: "Right now, Harry Kane is one year away from being worth that, if already not being worth that".
Mauricio Pochettino's side will be looking at this fixture with retribution on their minds, following the humiliating 5-1 defeat at St James' Park, on the last day of the 2015/16 season, which gifted second place in the league to Tottenham's North London rivals Arsenal.
With this additional time to reach greater levels of fitness and regain match sharpness, could Kane start the season in the same sort of fashion which he has finished the previous three?
Tottenham will hope to have Son fit with no new reinforcements now signed up for the new season.
Right-back is a particular priority for Spurs, who will be without Kieran Trippier for the first two weeks of the season.
The 27-year-old understands that the clock is ticking and that, more importantly, Spurs don't come across as a club capable of claiming silverware.
Four Spurs players made it into the PFA Team of the Year last season but Christian Eriksen was not one of them despite arguably being the clubs best player from January onwards. With other clubs in the top six improving, it's vital that Spurs improve with them or they could find themselves falling lower in the league.
Mauricio Pochettino and his squad will be keen to avenge that scoreline but their preparations have been knocked back following Danny Rose's public outburst on Thursday. So can they fill it in every game?