According to eye witness report, people screaming for help after the high-rise fire in Grenfell Tower on the Lancaster West Estate.
London Fire Commissioner Dany Cotton told reporters on Wednesday morning that there have been "number of fatalities", but said many had been rescued. She said her friend jumped. Reports indicate that the residents of the building had complained about fire safety issues earlier but no action was taken. According to local police, the residents were evacuated from the burning building. George Clarke is the British architect, and he lives near the tower.
"We have sent a number of resources to the scene including our hazardous area response team and over 20 ambulance crews", said Stuart Crighton, London Ambulance Service assistant director of operations.
Another witness named as Jody Martin told the BBC that he battled his way his way to the second floor only to encounter choking smoke.
"It's clearly been a devastating fire", he said. "He came to the window, and there was fire all around where his flat was", said Mnemimeh. "The building was too big".
The fire brigade said 40 fire engines and 200 firefighters are working to put out the blaze in the Tower, which has 120 flats.
London Fire Brigade said the cause of the fire was still being investigated, but several residents reported one man had said it started in his faulty fridge.
The sounds of sirens and helicopters is non-stop as locals and residents, evacuated from the building, begin to gather outside to watch the blaze.
He said he struggled to find an entrance to the building when he arrived about 1:00am and had to break an apartment window to get in.
There is no confirmation on what exactly caused the fire, though a resident reportedly said that an explosion was heard.
"[There were] big, big chunks of sheet metal coming down hitting the ground".
Several people have been killed in a burning tower after a huge fire engulfed a large block of flats.
They said official advice in the event of a fire had been to stay inside. In a statement posted on Facebook, the service said the "fire is from the second floor to the top floor".
The Mayor of London said questions will need to be answered over the safety of tower blocks across the city. They also added they moved people with injuries from the tower block to the hospital.
A woman showed up in tears looking for her sister, who lived in the 24-story building that caught fire.
"I went inside, grabbed my little girl and my girlfriend, and ran".
They also said that they could hear residents screaming for help from their windows. "There's nothing ... you're just helpless".
"There was a lot of people there - children, elderly people and disabled people; my family members, who thankfully made it out".
Good Morning Britain news correspondent Jonathan Swain said burning falling debris was making it hard and dangers for firefighters, and he could see people trapped in the building.