About 21,000 people, including many children and teenagers, were at the venuewhen a suicide bomber detonated an explosion at the end of a concert by U.S. singer Ariana Grande at 10.33pm on Monday (May 22).
The schoolgirl had been at the concert with her mother, Lisa Roussos, and sister, Ashlee Bromwich, in her 20s, from Leyland, Lancashire.
"It is with enormous sadness that it appears that one of the people who lost their lives in Monday's Manchester attack was one of our students here at Runshaw College", the statement read.
"News of Saffie's death in this appalling attack has come as a tremendous shock to all of us and I would like to send our deepest condolences to all of her family and friends", said Chris Upton, the head teacher at Tarleton Community.
As news of the violence spread, family members descended on the arena and swarmed local hospitals in search of loved ones. He said she was quiet and creative.
"The thought that anyone could go out to a concert and not come home is heartbreaking", he said.
The first victim to be publicly named Tuesday was Georgina Callander, 18, a student at Runshaw College in England.
Callander and Grande in 2015. On Tuesday, the school posted a statement on Facebook acknowledging that the attack had claimed a member of their community.
A 23 year old man was arrested in South Manchester in connection with the attack - but he's not been identified yet.
"Our deepest sympathies, thoughts and prayers go out to all of Georgina's friends, family, and all of those affected by this loss", the statement added.
Bishop Rawstorne Church of England Academy added that Georgina was a "very lovely young student who was very popular with her peers and the staff".
"Following the shocking events in Manchester yesterday, we have been informed that one of our former students, Georgina Callander has died as a result of injuries sustained".
Bolton Wanderers Football Club has paid tribute to Georgina, who had played for their under-11 girls' team in 2010, BBC reported. "Heaven has gained an angel.My thoughts and prayers are with you, your family, and your friends", David wrote.
After the attack, dubbed as "sickening" by Prime Minister of the United Kingdom, Theresa May, 12 of the 59 casualties taken to hospital were under the age of 16, David Ratcliffe of the North West Ambulance Service confirmed.
The 18-year-old had tweeted at the pop star the day before the concert.
"SHE WAS SO CUTE ANS LOVLEY I HUGGED HER SO TIGHT AND SHE SAID SHE LOVED MY BOW I CANT GET OVER THIS I NEVER WILL", Callander said in the post. She says the cast of "Once Upon a Time" is discussing a larger tribute to victims in Manchester that could involve a charitable donation. "If I can help with the funeral costs please can her family let me know. money is no painkiller just want to help".