"There's so much shock, anger and hurt that we feel today", he said.
He then described the incident as an evil act. Our first thoughts are with the families of those killed and injured.
"We are grieving today but we are strong".
Mr Burnham said: "I want Greater Manchester to be a digital city with a difference, one with a bold digital economy which actively encourages businesses to invest and grow and also one where technology is used to deliver positive change, from connecting young people with opportunities to tackling social problems such as homelessness".
Thousands are expected to attend the vigil which will be held at 6pm tonight in Manchester's Albert Square.
The former health secretary thanked the hundreds of emergency services personnel who worked through the night in the most "difficult circumstances imaginable", and those who had offered their support from other cities and countries.
The Mayor, Cllr Cathy Kent, has written a letter to Mayor Andy Burnham today expressing her condolences and committing our support as a borough to the people of Manchester. Even in the minute after the attack, they opened their doors to strangers and drove them away from danger.
"We have to ensure that terrorism never wins".
"My deepest sympathies are with the victims, and with families who have lost loved ones, as well as those desperately waiting for news".
THURROCK Council today (Tuesday 23 May) lowered its flags outside the Civic Offices in Grays as a mark of respect and act of solidarity with the people of Manchester after the horrific attack last night. My thoughts are with families and friends of those who have died and been injured.
"I can't think of anything that matches the horror of what happened last night".
"I have spoken with the prime minister and we have agreed that that all national campaigning in the general election will be suspended until further notice".